Company description
Thrombin is a member of the trypsin family of S1 peptidases. It catalyses the preferential cleavage of arginine-lysine bonds, converting fibrinogen to fibrin, and releasing fibrinopeptides A and B. Thrombin can itself cleave the N-terminal fragment of prothrombin, prior to its activation by factor Xa. Its effects are mediated by the thrombin receptor.
