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It works best if Sildenafil Generic taken approximately one hour before s**ual activity. To get an erection, you will need to be s**ually stimulated. Doctors usually recommend taking 100 mg per day, but the dosage can be decreased to 25 mg or increased to 100 mg if needed. Do not take more than one dose every 24 hours. It cannot be taken at the same time as other medications used to treat male erectile dysfunction problems. You should not take it with a high-fat meal, because it can reduce the effectiveness of the medication. It does not protect you from s**ually transmitted diseases.