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Definition of Tramadol:
Tramadol is a strong pain medicine used to treat moderate to severe pain that is not relieved by other types of pain medicines. Tramadol is a synthetic opioid and acts in the brain and spine (central nervous system) to reduce the amount of pain you feel.
Tramadol is a centrally acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
Key fact of Tramadol:
It is possible to become addicted to tramadol, but your doctor will explain how to reduce those risks.
If you need to take tramadol for more than a few weeks, your treatment plan may include details about how and when to stop taking this medicine.
It is best not to drink alcohol with tramadol as you are more likely to have side effects like sleepiness.
If tramadol makes you sleepy, dizzy, or clumsy or your vision is blurred, or unable to concentrate or make decisions, do not drive a car, ride a bike, or use tools or machinery.
Tramadol is also called by the brand names Invodol, Larapam, Mabron, Maneo, Oldaram, Tilodol, Tradorec and Zeridame.
Compositions of Tramadol:
When first approved in 1995, tramadol was not considered an opiate (like morphine or oxycodone), even though it worked in a similar way. However, because there were cases of abuse and addiction associated with its use, the thinking and warnings changed. In 2014, the FDA designated tramadol as a controlled substance. This means that although it has accepted use in medical care, it also has the potential for abuse or addiction and is therefore more tightly regulated. For example, a doctor may only prescribe a maximum of five refills, and a new prescription is required every 6 months.
Compared to other controlled substances, Tramadol is on the safe end of the spectrum. Heroin, for example, is a Schedule I drug (with high abuse potential and no approved medical use). OxyContin is a Schedule II drug (it also has a high potential for abuse, but has no approved medical uses). Classified as a Schedule IV drug, tramadol is considered useful as a pain reliever with a low potential for abuse.
Despite these concerns, tramadol is one of many common treatments recommended for osteoarthritis and other painful conditions. Many professional societies, including the American Academy of Orthopedic Surgeons, include it in their guidelines as a recommended medication for osteoarthritis.
Combination with SSRIs/SNRIs, SRAs, and serotonin-receptor agonists may indicate potentially fatal serotonin conditions. Adrenergic storms can also occur when combined with MAOIs. The use of tapentadol with alcohol or other narcotics such as benzodiazepines, barbiturates, nonbenzodiazepines, phenothiazines, and other sedatives can cause extended interruption, sedation, respiratory distress, and death.
Tapentadol 100mg is used by the liver chemicals CYP2C9, CYP2C19, and to a lesser extent CYP2D6, so it naturally interacts with drugs that interact with at least one of these activators as well as substrates of these proteins. Improvement or inhibition of movement/expression. (due to the rivalry complex); Some catalytic mediators/substrates require dosage optimization for one or both drugs.
The IUPAC name of Tramadol 50mg is 2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol and the chemical formula is (C16H25NO2) with a molecular weight of 263.381 g/mol.
The chemical structure of Tramadol (C16H25NO2) is given below.
Chemical structure of Tramadol (C16H25NO2)
Drug interaction of Tramadol:
Tramadol oral tablet can interact with other medications, vitamins, or herbs that you may be taking. Interactions occur when a substance changes the way a drug works. This can be harmful or prevent the medicine from working well.
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